What is AKK?
Akkermansia muciniphila
(commonly abbreviated as AKK) is widely regarded as one of the most promising next-generation probiotics. In 2004, it was first isolated from human feces by Dutch researchers Muriel Derrian and Willem de Vos. AKK are residents of the human gut microbiota, growing by utilizing gastrointestinal mucins as their sole carbon and nitrogen sources,and accounting for about 1-5% of the human microbiota. The abundance of AKK in the gut is related to the host's age, diet, and health status. Numerous studies have shown that the lack or decreased abundance of this probiotics was linked with multiple diseases (such as obesity, diabetes, liver steatosis, inflammation and response to cancer immunotherapies). AKK have demonstrated significant effects in regulating the intestinal barrier, weight management, blood sugar reduction, and anti-aging Furthermore, inactivated AKK has biological effects similar to,or even better than live AKK.
What is AM06TM?
In 2023, the technical team published a latest research finding in Microbiology Spectrum.
A systematic safety evaluation, including comprehensive assessments of general characteristics, genetic characteristics, tolerance, toxicity, etc., was carried out on 31 Akkermansia muciniphila isolates from healthy individuals (30 isolates from feces and 1 isolate from breast milk). It was discovered that the AM06 strain isolated from breast milk has advantages such as low toxicity, high genetic stability, and high tolerance to pH and bile salts, making it a candidate probiotic.
References：[1]Hou, F., Tang, J., Liu, Y, et al. Safety evaluation and probiotic potency screening of Akkermansia muciniphila strains isolated from human feces and breast milk [J]. Microbiology spectrum, 2023,11(2): e0336122
WHY AM06TM?
Self-affirmed GRAS
Exclusive AKK strain isolated from breast milk
Produced in accordance with US cGMP guidelines
Patented strain
22 patent applications,
8 patents granted,
3 PCT patents,
1 US patent application
Scientific data support
8 in vivo and in vitro functional validation studies
2 complete toxicology and safety studies
Clinical trials in progress
3 published papers
High-level production & quality standard
PROFORCARE® Heat-InActived technology, keep the bacteria intact and the active ingredients highly preserved.
U.S. FDA "postbiotic drug" level quality control
Strong stability
Shelf life 36 months at room temperature.
Third-party tested
by CNAS accredited laboratory
SPECIFICATION
PRODUCT |
SPEC |
CHAR |
APPLICATION |
Akkermansia muciniphila AM06TM
Inactivated bacteria powder
|
≥1.0× 1011cells/g |
White to light grey powder |
Tablet,
Capsule,
Powder |
≥2.0× 1011cells/g
|
≥5.0× 1011cells/g
|
RECOMMENDED FUNCTIONAL DIRECTION
GLP-1 Companion Akkermansia MuciniphilaWeight Management Capsule
Ingredients: Akkermansia muciniphila , Dihydroberberine, Aframomum melegueta extract, Black ginger extract, Vitamin B2, Vitamin D, L-Carnosine Zinc
Maintain healthy body weight and support healthy glucose and lipid metabolism
●Activates the body's ability to produce GLP-1, efficiently regulates glucose and lipid metabolism, stabilises blood sugar and reduce fat accumulation
●Suppresses appetite and reduces intake at source
●Activates Brown adipose tissue, inhibits lipid synthesis, accelerates fat decomposition and metabolism
●Akkermansia muciniphila repairs and strengthens the intestinal barrier, improves the intestinal microenvironment and creates a light and lean body shape
Net Quantity: 0.35g/capsule, 60 capsules/bottle
Directions: Twice daily, 1 capsule each time
GlucoEase Capsule
Ingredients: Akkermansia muciniphila , Dihydroberberine, Mulberry leaf extract, Black ginger extract, Chromium-enriched yeast
Regulate blood sugar metabolism and maintain healthy blood sugar level
●Activates the body's ability to produce GLP-1, enhance insulin secretion, and efficiently regulate blood sugar metabolism
●Inhibits α-glucosidase activity and reduces intestinal absorption of sugar
●Promotes cellular glucose uptake and utilization, reducing glucose levels in the blood.
●Repairs and strengthens the intestinal barrier, optimize the intestinal microecological environment, improve insulin sensitivity, and builds long-term blood sugar homeostasis
Net Quantity: 0.35g/capsule, 60 capsules/bottle
Directions: Twice daily, 1 capsule each time
Akkermansia Muciniphila With Poly-Prebiotic Capsule
Ingredients: Akkermansia muciniphila, Inulin, Fructooligosaccharides, Blueberry extract, resistant Starch
Strengthen the intestinal barrier and maintain gut health
●Akkermansia muciniphila promotes the repair of the intestinal mucus layer and enhances the barrier function of the gut
●Akkermansia muciniphila and prebiotics boost gut immunity and support overall immune health
●Akkermansia muciniphila stimulates GLP-1 secretion, promotes glucose and lipid metabolism ，and helps maintain a healthy weight
Net Quantity: 0.35g/capsule, 60 capsules/bottle
Directions: Twice daily, 1 capsule each time
PQQ Neuro Vitality Plus Capsule
Ingredients: Akkermansia muciniphila, lnulin, Fructooligosaccharides.Blueberry extract, Resistant Starch
Anti-aging and brain protection, rejuvenating youthful mental energy
●Protects and repairs mitochondria, revitalizes cellular vitality, and enhances cellular energy metabolism.
●Reduces anxiety and depression, and improve sleep quality
●Supplements brain nutrition, improves neurotransmission and memory functions, enhances brain cognitive ability
●Reduces free radical damage and delay cellular aging.
Net Quantity: 0.33g/capsule, 120 capsules/bottle
Directions: Twice daily, 2 capsules each time
